Effect of polyherbal formulation for immunomodulation in immunosuppressed mice
Author(s): Pratibha Sonawane, Rasiklal M, Dr. Jitendra Kandale and Dr. Santosh Bhujbal
Abstract: A Polyherbal Formulation is prepared by using Methanolic extract of Sphaeranthus indicus flowerheads, fruits of Piper nigrum, Hydroalcoholic extracts of Withania somnifera, Ocimum sanctum, Centella asiatica for immunomodulatory activity. The effects of 100mg, 200mg, 400mg were screened on humoral and cellular immunity i.e. HA titer and Delayed Type Hypersensitivity on immunosuppressed mice. The present study demonstrated that the formulation200mg, 400mg have synergistic immunostimulant activity in HA titer and DTH, and it also showed protection against cyclophosphamide induced immunoosupression.
Pratibha Sonawane, Rasiklal M, Dr. Jitendra Kandale, Dr. Santosh Bhujbal. Effect of polyherbal formulation for immunomodulation in immunosuppressed mice. Int J Pharmacognosy Life Sci 2022;3(1):19-23. DOI: 10.33545/27072827.2022.v3.i1a.42