In vitro spasmodic & antispasmodic effect of Amaranthus spinosus L. & Amaranthus viridis L. on isolated chicken ileum
Author(s): Dr. Lakshmi Kanta Kanthal, Dr. Suman Pattanayak, Rimi Mondal, Purnendu Pramanick, Devprakash Majhi, Sarjina Ansari and Md Rajibul Islam
Abstract: Many useful chemicals and/or medications are derived from medicinal plants. According to the International Union for Conservation of Nature and the World Wildlife Fund, around 50,000 to 80,000 blooming plants are used medicinally. Amaranthus spinosus is used as an expectorant and to relieve breathing in severe bronchitis in Malaysia. It is also used as a sudorific, febrifuge, antidote to snake poison, galactagogue, and to treat menorrhagia in mainland South-East Asia. Some Indian tribes use Amaranthus spinosus to induce abortion. Traditional medicine use Amaranthus viridis to treat fever, pain, asthma, diabetes, dysentery, urinary problems, liver disorders, eye disorders, and venereal illnesses. The herb also has antibacterial qualities.
The purpose of this study was to investigate the antispasmodic effects of methanolic root extracts of
Amaranthus spinosus and
Amaranthus viridis on an isolated chicken ileum. Maceration was used to make methanolic root extracts of the plant material. The antispasmodic activity was tested in vitro (37
oC, pH 7.4 with continuous oxygenation). Both plants elicited spontaneous relaxation of the chicken ileum, with the greatest impact at 0.8 ml and 0.1 ml, respectively. This reveals that aqueous and cruder root extracts of
Amaranthus spinosus and
Amaranthus viridis have a spasmolytic action on isolated chicken ileum, hence validating its folkloric use in the treatment of gastrointestinal diseases.
DOI: 10.33545/27072827.2023.v4.i2b.98Pages: 128-134 | Views: 179 | Downloads: 78Download Full Article: Click Here
How to cite this article:
Dr. Lakshmi Kanta Kanthal, Dr. Suman Pattanayak, Rimi Mondal, Purnendu Pramanick, Devprakash Majhi, Sarjina Ansari, Md Rajibul Islam.
In vitro spasmodic & antispasmodic effect of Amaranthus spinosus L. & Amaranthus viridis L. on isolated chicken ileum. Int J Pharmacognosy Life Sci 2023;4(2):128-134. DOI:
10.33545/27072827.2023.v4.i2b.98
