Respiratory diseases, including asthma, bronchitis, chronic obstructive pulmonary disease (COPD), and pneumonia, are among the leading causes of morbidity and mortality worldwide. Both allopathic and herbal systems of medicine play significant roles in their management. The present study provides a comparative analysis of allopathic and herbal medicines in treating respiratory disorders, focusing on their mechanisms of action, therapeutic efficacy, side effects, and patient compliance. Allopathic drugs, such as bronchodilators, corticosteroids, and antibiotics, offer rapid symptom relief and targeted action, whereas herbal formulations derived from plants like Adhatoda vasica, Glycyrrhiza glabra, Zingiber officinale, and Ocimum sanctum provide holistic and long-term benefits with fewer adverse effects. The study emphasizes that while allopathic medicines are indispensable for acute management, herbal therapies can serve as effective adjuncts or alternatives in chronic respiratory care. Integrating both systems through evidence-based approaches can enhance therapeutic outcomes and minimize drug-related complications.